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J INTERN MED: The relationship between lipoprotein (a) and SARS-CoV-2 infection

 Last Update: 2021-06-16
 Source: Internet
 Author: User

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Complications including ischemic heart disease (IHD) aggravate the condition after SARS-CoV-2 infection
.

High lipoprotein (a) [Lp (a) ] levels IHD and thrombotic a strong risk factor for embolic events

Infected thrombus

Recently, a research article was published in the Journal of Internal Medicine, an authoritative journal in the field of internal medicine.
Researchers aim to assess whether SARS-CoV-2 infection changes the risk of high Lp(a) concentrations in predicting IHD or thromboembolic events
.

The researchers used the British Biobank to conduct a cohort study on data during the SARS-CoV-2 pandemic, and compared the baseline Lp(a) levels of SARS-CoV-2 positive patients and the population control group
.

The British Biobank has obtained ethical approval from the Northwest Multi-Center Research Ethics Committee (REC:11/NW/0382)

The relationship between Lp(a), SARS-CoV-2, IHD and thromboembolic events

The Lp(a) concentration of SARS-CoV-2 positive patients was similar to that of the control group
.

In population controls (n=435104) and SARS-CoV-2 positive patients (n=6937), as the concentration of Lp(a) increases, the risk of IHD increases

It can be seen that SARS-CoV-2 infection strengthens the correlation between high Lp(a) levels and IHD, but Lp(a) does not affect the risk of thromboembolic events

SARS-CoV-2 infection reinforces the correlation between high Lp(a) levels and IHD, but Lp(a) does not affect the risk of thromboembolic events

Original source:

Silvia Di Maio.

Lipoprotein (a) and SARS-CoV -2 infections: susceptibility to infections, ischemic heart disease and thromboembolic events in this message

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