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    Home > Active Ingredient News > Immunology News > J Invest Dermatol: Oral administration of dimethyl fumarate to target HCA2 expression in an imiquimod mouse model

    J Invest Dermatol: Oral administration of dimethyl fumarate to target HCA2 expression in an imiquimod mouse model

    • Last Update: 2022-04-16
    • Source: Internet
    • Author: User
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    Figure 1: DMF treatment reduces epidermal thickness in an HCA2-dependent manner


     

    (A) Representative HE section of mouse dorsal skin on day 13


     

    Figure 2: Keratinocytes are potential targets for the protective effects of oral DMF


    (A) Representative H&E stained section of Aldara®-treated chimera dorsal skin





    Source: Suhrkamp I, Morrison PJ, Assmann JC, ORAL DIMETHYL FUMARATE TARGETS HCA-EXPRESSING SKIN CELLS IN THE IMIQUIMOD MOUSE MODEL.




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