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    Home > Active Ingredient News > Immunology News > J Korean Med Sci: In Korean children between 6 and 35 months of age, immunity declined six months after the triple and four-price flu vaccinations.

    J Korean Med Sci: In Korean children between 6 and 35 months of age, immunity declined six months after the triple and four-price flu vaccinations.

    • Last Update: 2020-10-12
    • Source: Internet
    • Author: User
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    Antibody titration caused by influenza vaccines decreases over time, and younger children have lower immunogenicity and shorter immunization times.
    this study aims to compare the persistence of antibodies in children 6 to 35 months after being vaccinated against influenza, based on influenza strains, vaccine types, antigen doses, and initial status, and has been published online in J Korean Med Sci.
    From September to December 2016, researchers selected 124 healthy children between 6 and 35 months of age at 10 hospitals in South Korea and randomly assigned a full dose of the four-price flu vaccine or a half-dose of the Victoria B strain triple-price influenza vaccine.
    blood clot inhibits antibody titration (a measure of serum protection rate) of recommended influenza strains 6 months after vaccination.
    results showed that the serum protection rates of A(H1N1, H3N2, B) and B Victoria were 88.7%, 97.4%, 36.6% and 27.6%, respectively, after six months. Serum protection rates of
    A (H1N1), A (H3N2) and B (Victoria) were 91.4 per cent, 98.7 per cent and 27.5 per cent in full-dose four-price vaccines, respectively, and 83.7 per cent, 94.6 per cent and 27.9 per cent in half-dose trialose vaccines, respectively.
    protection rate of B (mountain) strains in the four-price group was 23.8%, and the three-price group was 14.0%.
    , the results show that after 6 months, the persistence of antibodies is more beneficial to influenza A strains than to influenza B strains.
    four-pyr price vaccine group was more persistent against additional B strains at 6 months.
    children who were vaccinated against different B strains were no better immune than those who were not vaccinated against another B strain.
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