J Neurosci: Study reveals the neurological principles behind tickling behavior.

September 9, 2020 /--- According to a recent study based on mouse models published in journal of Neuroscience, rubbing the skin can effectively activate the itch-stopping signaling pathway in the nerves of the spinal cord.
even scratching and scratching of skin tissue can damage the skin, especially in sensitive areas such as the eyes, and become insignificant relative to its itching relief.
, gentle touch can also reduce itching compared to severe scratching behavior.
study, the authors looked at the neural path path paths behind this less destructive caressing behavior to relieve itching.
(Photo: www.pixabay.com) first stimulated mouse scratching by using a chemical that causes itching beneath the skin tissue of mice.
, the team recorded the electrical response of neurons in the back of the spinal cord as they stroked the animals.
mice, neurons emit more frequently and neurons emit less frequently after stroke.
these neurons respond to both tactile and itching, so they correspond to increased tactile sensations, not itching, which helps to relieve itching.
the same reduction when the team directly stimulated touch-sensing neurons under the skin.
, one of the neurons in the spinal cord that inhibits the sensational neurons and the anti-itch neurons does not have the effect of reducing the reaction of the back-angle neurons.
results show that caressing triggers cascading reactions, activating sensory neurons under the skin, and then activating itching intermediate neurons in the spinal cord, leading to reduced back-angle nerve activity and eventually reduced itching.
(bioon.com) Source: Rubbing activate skins itch-relief neural pathway Original source: Low-Threshold Mechanosensitive VGLUT3-Lineage Sensory Neurons Mediate Spinal Regency of Itch by Touch, JNeurcios (2020). DOI: 10.1523/JNEUROSCI.0091-20.2020.