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J PINEAL RES: What should I do if the hormone metabolism disorder of the "community animals" who work overtime late at night?

 Last Update: 2021-12-26
 Source: Internet
 Author: User

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Artificial lighting (LAN) at night in today's society has become a common practice
.

LAN is introduced in different regions, at different times, and at different intensities, and it is closely related to metabolic disorders

Artificial lighting (LAN) at night in today's society has become a common practice

The effects of light and melatonin on hormones and metabolites are contradictory in the literature

Nine healthy male participants (26±1.
3 years old, body mass index 24.
8±0.
8 kg/m ² ) were randomly divided into three crossover design schemes: light (>500 lux ) (LS), dark light (<5 lux ) + Exogenous melatonin (DSC) and light (>500 lux ) + exogenous melatonin (LSC)
.

During each clinical treatment period, all subjects were awake in a semi-recumbent position, starting from 18 hours and ending at 06:00 the next day

Nine healthy male participants (26±1.

Hormones and metabolites before and after meals

Hormones and metabolites before and after meals Hormones and metabolites before and after meals Hormones and metabolitesbefore and after meals Hormones and metabolites before and after meals

The results showed that compared with LS, participants had significantly lower blood glucose, insulin, and TAG levels in the presence of melatonin (LSC and DSC) (p=.
002, p=.
02, and p=.
007, respectively).
)
.

With the increase of melatonin, the pre-meal plasma NEFA of LS patients was significantly lower than that of DSC and LSC patients (p<0.

The results showed that compared with LS, participants had significantly lower blood glucose, insulin, and TAG levels in the presence of melatonin (LSC and DSC) (p=.

In summary, this study shows that melatonin can improve night-time glucose tolerance, insulin sensitivity, and blood lipid levels

references:

References: References: References:References:

Mohammed S.

Mohammed S.
Albreiki,Benita Middleton,Shelagh M.
Hampton, et al.
The effect of melatonin on glucose tolerance, insulin sensitivity and lipid profiles after a late evening meal in healthy young males .
First published: 28 September 2021 https://doi .
org/10.
1111/jpi.
12770.
Mohammed S.
Albreiki,Benita Middleton,Shelagh M.
Hampton, et al.
The effect of melatonin on glucose tolerance, insulin sensitivity and lipid profiles after a late evening meal in healthy young males .
First published : 28 September 2021 https://doi.
org/10.
1111/jpi.
12770.
Mohammed S.
Albreiki,Benita Middleton,Shelagh M.
Hampton, et al.
The effect of melatonin on glucose tolerance, insulin sensitivity and lipid profiles after a late evening meal in healthy young males .
First published: 28 September 2021 https://doi.
org/10.
1111/jpi.
12770.
Mohammed S.
Albreiki,Benita Middleton,Shelagh M.
Hampton, et al.
The effect of melatonin on glucose tolerance, insulin sensitivity and lipid profiles after a late evening meal in healthy young males .
First published: 28 September 2021 https://doi .
org/10.
1111/jpi.
12770.
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