J Thorac Oncol: The impact of low-dose CT (LDCT) screening for primary lung cancer on the risk of subsequent brain metastasis (BM).

Brain metastasis (BM) is one of the most common metastatic sites of primary lung cancer.

Brain metastasis (BM) is one of the most common metastatic sites of primary lung cancer.

The study used the NLST database to include 1502 patients diagnosed with lung cancer from 2002 to 2009, and followed up to observe the occurrence of BM.

The study used the NLST database to include 1502 patients diagnosed with lung cancer from 2002 to 2009, and followed up to observe the occurrence of BM.

 research summary

Compared with lung cancer patients detected by other methods, the incidence of BM in lung cancer patients found in LDCT screening was lower at 3 years (6.

Compared with lung cancer patients detected by other methods, the incidence of BM in lung cancer patients found in LDCT screening was lower at 3 years (6.

Risk of BM in different groups1

Sensitivity analysis found that compared with chest X-ray, LDCT can reduce the risk of BM (HR = 0.

In summary, based on large-scale population studies, low-dose CT (LDCT) screening for early detection of primary lung cancer (PLC) can reduce the risk of brain metastasis (BM) after the diagnosis of PLC.

Original source:

Su CC, Wu JT, Neal JW, et al.

Su CC, Wu JT, Neal JW, et al.
Impact of Low-Dose CT Screening for Primary Lung Cancer on Subsequent Risk of Brain Metastasis, Journal of Thoracic Oncology (2021), doi: https://doi.
org/10.
1016/ j.
jtho.
2021.
05.
010.


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