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    Home > Active Ingredient News > Antitumor Therapy > JAAD: Indications for radiation therapy to treat skin cancer

    JAAD: Indications for radiation therapy to treat skin cancer

    • Last Update: 2021-09-11
    • Source: Internet
    • Author: User
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    In 1990, radiotherapy was first used to treat patients with squamous cell carcinoma of the nose of the skin (cSCC), although with the development of dermatology and surgical techniques, such as Morse Microsurgery (MMS), radiotherapy was used in the diagnosis and treatment of skin malignant tumors.
    The role gradually weakened
    .


    But in some cases, radiation therapy still has irreplaceable advantages


    Diagnosis and treatment

    JAAD's September 2021 continuing education section reviewed the role of radiotherapy in the treatment of skin nausea tumors, including diagnosis and application
    .


    This article focuses on compiling its part on indications


    diagnosis

    Indications for radiotherapy:

    Indications for radiotherapy:

    l Radiotherapy is an alternative therapy for patients with skin cancer who cannot undergo surgery or who refuse surgery

    l Adjuvant radiotherapy for aggressive tumors after surgery to reduce the risk of recurrence

    l Palliative radiotherapy can control local symptoms or relieve symptoms for patients who cannot heal or are in advanced stages
    .

    Radiotherapy can preserve unaffected tissue near the tumor

    Radiotherapy can preserve unaffected tissue near the tumor

    It is suitable for large or locally advanced tumors.
    In these tumors, further surgery may lead to increased recurrence rate, impaired function or poor cosmetic effect
    .

    Cutaneous squamous cell carcinoma (cSCC) of radiation therapy
    .


    A, a 95-year-old malewith 5 cm cSCC on theforehead and scalp (radiation field is marked in black)


    Cutaneous squamous cell carcinoma (cSCC) of radiation therapy


    B, 4 weeks after irradiation with 20 doses of 50 Gy


    For younger patients, a lower dose of radiation is given to the lesion for a longer period of time to minimize late side effects, and at the same time, the effect of controlling local symptoms will be better
    .


    But it should also be informed of alternatives, because of the risk of developing secondary malignancies


    Adjuvant radiotherapy can be used as a supplementary treatment for advanced disease

    Adjuvant radiotherapy can be used as a supplementary treatment for advanced disease

    It can reduce the wind direction of local or regional recurrence after surgery
    .


    This option can be used for positive surgical margins and tumors that cannot be further removed, usually within 4 to 8 weeks after surgery


    Adjuvant radiation therapy of CSCC
    .


    A, a 77-year-old woman withmultiple recurrent cSCCs on theright lower eyelid with obvious perineural infiltration, had previously undergone MMS surgical resection,partialrightmaxillary resection , right infraorbital nerve resection, and pterygopalatine fossa to skull base Anatomy.


    Adjuvant radiation therapy of CSCC


    Adjuvant radiation therapy of microcapsules adnexal carcinoma
    .


    A, a 55-year-old woman with recurrent microcystic adnexal carcinoma, with obvious perineural infiltration on the left face and left ear
    .

    Adjuvant radiation therapy of microcapsules adnexal carcinoma
    .
    A, a 55-year-old woman with recurrent microcystic adnexal carcinoma, with obvious perineural infiltration on the left face and left ear
    .
    Adjuvant radiation therapy adjuvant radiation therapyadjuvant radiation therapyof microcapsules adnexal carcinoma microcapsules adnexal carcinomamicrocapsules adnexal carcinoma
    .
    A,A,A 55 year old woman, suffering from recurrent cancer microcapsules accessory, the left face and left ear significant peripheral nerve infiltration of perineural spreadperineural spread
    .

    B.
    Immediately perform surgical resection with MMS , including left parotidectomy and anatomy of the left neck, to obtain a clear edge
    .

    B.
    Immediately perform surgical resection with MMS , including left parotidectomy and anatomy of the left neck, to obtain a clear edge
    .
    B, B,immediately performed MMS MMS for MMS forsurgery, including a left PAROTIDECTOMY PAROTIDECTOMY PAROTIDECTOMYanatomical neck surgery and left to obtain sharp edges
    .

    C, Two years after reconstruction of forearm free skin flap , the auxiliary radiation dose was 60 Gy, and the lymph nodes on the left side of the face and the ipsilateral neck were irradiated in 30 times .

    C, Two years after reconstruction of forearm free skin flap , the auxiliary radiation dose was 60 Gy, and the lymph nodes on the left side of the face and the ipsilateral neck were irradiated in 30 times .

    C, C,forearm free flap free flap free flapreconstruction aftertwo years, the auxiliary radiation dose is 60 Gy, 30 minutes and left face irradiation ipsilateral cervical lymph nodes cervical lymph nodes cervical lymph nodes
    .

    Palliative radiotherapy is used for advanced or incurable diseases (including skin metastases)

    Palliative radiotherapy is used for diseases that are late or incurable

    Palliative radiotherapy can relieve local symptoms or control lesions, relieve symptoms, and improve the quality of life of patients
    .
    These tumors usually affect the patient's quality of life due to pain, infection or bleeding
    .
    The dosage regimen and segmentation plan depend on tumor size, location, patient life expectancy, and expected adverse effects of treatment
    .

    Infect

    The usual treatment regimen for patients with non-melanoma skin cancer is 30 Gy, 10 times in 2 weeks, or 45-50 Gy, 18 to 25 times in 4 to 5 weeks
    .
    1 For patients who are in poor health and do not need long-term cosmetics, a single large dose of 20 Gy can be given
    .

    Clinical problems that need to be resolved before radiotherapy

    Clinical problems that need to be resolved before radiotherapy

    Where is the tumor located? Is it in a high-risk anatomical area (near the eyelids, nose, ears, and lips)?

    Is the histological diagnosis sufficient?

    Has the appropriate installment been completed?

    Will this lesion recur?

    Has the patient received any treatment for this lesion? If so, what treatment was performed? These treatments are as effective as songs?

    What treatments (if any) are planned?

    What is the expected goal of radiotherapy-primary treatment or adjuvant treatment? Curative or palliative?

    Has the patient received any radiation therapy before? If so, which part is being treated? What is the duration-it is best to know what the therapeutic dose is? Which institution did the treatment? How long before the treatment was completed?

    Does the patient have any other cancer diagnoses? If so, how are these conditions treated?

    What is the overall medical condition of the patient?

    What complications does the patient have?

    Does the patient have any medical history that may be worsened by radiation, such as CREST syndrome, skin fibrosis, lupus erythematosus or scleroderma?

    What do patients expect from radiotherapy?

     

     

     

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