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Diabetes mellitus (DM) can increase the embolism risk of non-valvular atrial fibrillation (NVAF).
Diabetic stroke
This study aims to evaluate whether prediabetes is related to the increased risk of stroke and death in patients with NVAF.
This study aims to evaluate whether prediabetes is related to the increased risk of stroke and death in patients with NVAF.
Researchers conducted a historical cohort study using Clalit Health Services electronic medical records.
diagnosis
Prognosis of patients with different blood glucose status
Prognosis of patients with different blood glucose statusA total of 44,451 patients were enrolled.
During an average follow-up of 38 months, the incidence of stroke (per 100 person-years) in normal blood glucose individuals, pre-diabetic patients, and diabetic patients were 1.
Cumulative incidence of stroke in patients with different blood glucose status
Cumulative incidence of stroke in patients with different blood glucose statusIn univariate and multivariate analysis, even after adjusting for CHA2DS2-Vasc risk factors and anticoagulant use, compared with normal blood sugar, patients with prediabetes still have a higher risk of stroke (adjusted hazard ratio [adjHR ]: 1.
Compared with people with normal blood sugar, patients with prediabetes still have a higher risk of stroke (adjusted hazard ratio [adjHR]: 1.
Estimated risk of death
Estimated risk of deathDiabetes patients have a higher risk of death (adjHR: 1.
In summary, in this group of NVAF patients, even after other recognized risk factors are included, prediabetes is also associated with an increased risk of stroke.
In this group of NVAF patients, even after including other recognized risk factors, prediabetes is also associated with an increased risk of stroke.
Original source:
Kezerle Louise, Tsadok Meytal Avgil, Akriv Amichay et al.
org/10.
1016/j.
jacc.
2020.
12.
030">Pre-Diabetes Increases Stroke Risk in Patients With Nonvalvular Atrial Fibrillation in this message
