JAHA: Coronary Artery Microvascular Dysfunction in Patients with Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is a systemic self- immune inflammatory disease, and premature atherosclerosis of arteries and heart blood vessels increased risk

Recently, a research article was published in JAHA, an authoritative journal in the field of cardiovascular diseases.

The study included consecutive SLE patients (n=42) who underwent cardiac positron emission tomography-computed tomography, and excluded patients with obstructive coronary artery disease and systolic dysfunction

MFR and burden of atherosclerosis in SLE patients

Although the burden of non-obstructive atherosclerosis was similar, compared with the control group, the overall MFR of SLE patients decreased significantly, and the prevalence of CMD was higher (1.

It can be seen that the prevalence of coronary vasomotor abnormalities in SLE patients with cardiac symptoms without obstructive coronary artery disease is high

Brittany N.