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JAHA: Serum growth differentiation factor 15 levels are associated with post-ischemic stroke depression

 Last Update: 2022-01-08
 Source: Internet
 Author: User

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Stroke is the main cause of death and long-term disability, and it has become an important global public health problem
.

Among all complications of stroke survivors, post-stroke depression (PSD) is the most common mental problem

Stroke quality of life

However, the effect of serum growth differentiation factor 15 (GDF-15) on PSD is still unknown
.

Recently, the heart blood vessels published a research article on the disease areas authoritative magazine JAHA, the purpose of this study was to investigate the correlation between serum levels of GDF 15-PSD patients with ischemic stroke

Blood vessel

The study is based on a random sample from CATIS (Chinese Acute Ischemic Stroke Antihypertensive Trial) and analyzed the GDF-15 levels of 572 patients from 7 participating hospitals
.

The result of the study was depressive symptoms (Hamilton Depression Scale score ≥ 8) that appeared 3 months after ischemic stroke

hypertension

A total of 231 (40.
4%) stroke patients in the study experienced PSD within 3 months
.

Compared with the lowest tertile, the multivariate adjusted odds ratio of PSD associated with the highest tertile of serum GDF-15 levels was 2.

It can be seen that the increase of serum GDF-15 level in the acute phase of ischemic stroke is independently related to PSD, indicating that GDF-15 level may be a valuable prognostic biomarker of PSD
.

The increase of serum GDF-15 level in acute phase of ischemic stroke is independently correlated with PSD, indicating that GDF-15 level may be a valuable prognostic biomarker of PSD
.

Original source:

Yuhan Zang,et al.

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