JAHA: The relationship between plasma omega-3 fatty acids and the risk of cardiovascular events in patients with acute coronary syndrome

In the primary prevention , the plasma ω3 polyunsaturated fatty acids (ω3-PUFAs) and medsci.

Recently, a research article was published in JAHA, an authoritative journal in the field of cardiovascular diseases, in this case cohort of 203 patients with cardiovascular deaths, 325 patients with myocardial infarction , 271 patients with ventricular arrhythmia, and 161 patients with atrial fibrillation In the study, the researchers assessed the subjects' basic plasma ω3-PUFA levels (α-linolenic acid, eicosapentaenoic acid, dodecosapentaenoic acid, and docosahexaenoic acid) through gas chromatography.

After the inverse probability weighted multivariate adjustment including all traditional risk factors, the proportion of long-chain ω3-PUFA (eicosapentaenoic acid, docosapentaenoic acid and docosahexaenoic acid) is relatively high , The probability of cardiovascular death was reduced by 18% (the odds ratio [OR] of [adj] adjusted for every 1 SD was 0.

There is a correlation between α-linolenic acid and subsequent cardiovascular disease probability (adj OR 0.

It can be seen that in patients with acute coronary syndrome , long-chain ω3-PUFA in plasma is negatively correlated with the reduced probability of sudden cardiac death, but has nothing to do with traditional risk factors and blood lipids .

Thomas A.