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Stroke is the fifth leading cause of death in the elderly and a common cause of severe long-term disability
.
Some prospective cohort studies have reported a significant association between total non-esterified fatty acid (NEFA) concentration and stroke events
Recently, a research article was published in JAHA, an authoritative journal in the field of cardiovascular diseases, in which researchers assessed the association between stroke events and serum concentrations of non-esterified saturated, monounsaturated, polyunsaturated, and trans fatty acids
.
Participants in the Cardiovascular Health Study (CHS) who had no stroke at baseline (1996-1997) and had an archived fasting serum sample (N=2028) were included in this study
.
The researchers used gas chromatography to quantitatively analyze 35 NEFAs
During a median follow-up of 10.
5 years, a total of 338 stroke events occurred
.
The total n-3 (hazard ratio [HR] of 0.
Thus, the study found that there are a total of 2 NEFA subtypes and 3 separate NEFAs associated with stroke
.
Among them, the NEFAn-3 subclass and the second high-γ-linolenic acid are derived from diet and may be potential biomarkers of overall stroke risk
The study found that there are a total of 2 NEFA subtypes and 3 separate NEFAs associated with stroke
Original source:
Neil K.
