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    Home > Active Ingredient News > Digestive System Information > JAHA: Transmethylamine-N-oxide is associated with cardiac fibrosis in HIV-infected persons

    JAHA: Transmethylamine-N-oxide is associated with cardiac fibrosis in HIV-infected persons

    • Last Update: 2021-08-13
    • Source: Internet
    • Author: User
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    People infected with HIV are at increased risk of diastolic dysfunction, heart failure, and sudden cardiac death, all of which are characterized by high levels of myocardial fibrosis


    Infect



    In the CHART-HIV study, 94 (48%) of 195 people had diastolic dysfunction; patients in this cohort had a higher prevalence of hypertension, hyperlipidemia, and chronic kidney disease, and TMAO and choline in plasma The level is higher


    immunity

    It can be seen that in this study of HIV-infected patients, the intestinal metabolite TMAO is associated with potential diffuse myocardial fibrosis and is considered a potential marker of early structural heart disease


    In this study of HIV-infected people, the intestinal metabolite TMAO was associated with potential diffuse myocardial fibrosis and was considered a potential marker of early structural heart disease


    Original source:

    Nalini A.


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