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    Home > Active Ingredient News > Infection > JAMA: 2-dose versus 3-dose hepatitis B vaccine causes no difference in acute myocardial infarction

    JAMA: 2-dose versus 3-dose hepatitis B vaccine causes no difference in acute myocardial infarction

    • Last Update: 2022-04-24
    • Source: Internet
    • Author: User
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    Newborns will be vaccinated against hepatitis B within 24 hours of birth, and the second and third doses will be given 1 month and 6 months later
    .


    But in the face of hepatitis B virus, many people will worry about whether they will be immune for life after injection of hepatitis B vaccine? During the physical examination, it is found that there is no hepatitis B antibody.


    Newborns will be vaccinated against hepatitis B within 24 hours of birth, and the second and third doses will be given 1 month and 6 months later


    People at high risk of hepatitis B need to monitor antibodies on a regular basis.


    myocardial infarction

    To compare acute MI rates between recipients of HepB-CpG vaccine and HepB-alum vaccine, scholars from the United States conducted a prospective cohort non-inferiority study, and the results were published in the journal JAMA
    .


    The study included 69,625 adults not on dialysis who received at least one dose of the hepatitis B vaccine between Aug.


    JAMA

    RESULTS: Among 31,183 HepB-CpG vaccine recipients (median age = 49 years; IQR, 38-56 years), 51.
    2% (n = 15965) were male and 52.
    7% (n = 16423) were Hispanic
    .


    Of the 38,442 HepB-alum recipients (median age, 49 years; IQR, 39-56 years), 50.


    After inverse probability treatment weighting, characteristics were well balanced across vaccine groups
    .


    Fifty-two type 1 acute MI events were confirmed in the population receiving the HepB-CpG vaccine, a rate of 1.


    Fifty-two type 1 acute MI events were confirmed in the population receiving the HepB-CpG vaccine, a rate of 1.


    Cumulative incidence of confirmed acute myocardial infarction among hepatitis B vaccine recipients

    Cumulative incidence of confirmed acute myocardial infarction among hepatitis B vaccine recipients

    In this cohort study, receiving the HepB-CpG vaccine did not meet the statistical criteria for an increased risk of acute myocardial infarction compared with the HepB-alum vaccine
    .

    In this cohort study, receiving the HepB-CpG vaccine did not meet the statistical criteria for an increased risk of acute myocardial infarction compared with the HepB-alum vaccine
    .


    In this cohort study, receiving the HepB-CpG vaccine did not meet the statistical criteria for an increased risk of acute myocardial infarction compared with the HepB-alum vaccine .


    references:

    Association Between 2-Dose vs 3-Dose Hepatitis B Vaccine and Acute Myocardial Infarction.


    JAMA.


    Association Between 2-Dose vs 3-Dose Hepatitis B Vaccine and Acute Myocardial Infarction.
    JAMA.
    Published online March 25, 2022.
    doi:10.
    1001/jama.
    2022.
    2540 Association Between 2-Dose vs 3-Dose Hepatitis B Vaccine and Acute Myocardial Infarction.
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