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    Home > Active Ingredient News > Endocrine System > JAMA Intern Med: Characteristics of prediabetes in older people and subsequent diabetes risk

    JAMA Intern Med: Characteristics of prediabetes in older people and subsequent diabetes risk

    • Last Update: 2021-02-24
    • Source: Internet
    • Author: User
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    Prediabetes refers to the "intermediate" state of high blood sugar but does not meet the criteria for diagnosis of diabetes, and is an early warning sign of diabetes.
    are at high risk of diabetes, but the characteristics of the elderly prediabetes population have not been fully studied.
    researchers recently compared the abnormality rate of prediabetes and the risk of subsequent diabetes under different prediabetes definitions.
    researchers collected data on 3,412 older participants without diabetes in the Community Atherosclerosis Risk study (Baseline 2011-13), follow-up to January 2016 with an average follow-up period of 5 For 0 years, prediabetes was defined as glycation of hemoglobin (HbA1c) levels of 5.7%-6.4%, abnormal peri-abdominal blood sugar (IFG, FG levels of 100-125mg/dl), or both.
    endpoint of the study was diabetes diagnosis (HbA1c≥6.5% or FG≥126 mg/dL).
    75.6 years, 60 per cent were women and 17 per cent were black.
    follow-up, 156 diabetes incidents occurred and 434 people died.
    1,490 participants (44%) had HbA1c at 5.7-6.4%, 1996 IFG (59%), a total of 2,482 met the definition of prediabetes, and 1004 had HbA1c and FG abnormalities (73%).
    for baseline HbA1c levels of 5.7-6.4%, 97 developed diabetes (9%), 148 blood sugar returned to normal (13%, HbA1c-lt;5.7%), and 207 people died (19%).
    baseline IFG population, 112 (8%) were diagnosed with diabetes, 647 had returned to normal oncercline blood sugar (44%, FG-lt;100 mg/dL), and 236 (16%) died.
    for those with baseline HbA1c levels below 5.7%, 239 (17%) developed HbA1c progression of 5.7-6.4% and 41 (3%) developed diabetes.
    for people with baseline FG levels below 100 mg/dL, 80 (8%) developed IFG and 26 (3%) developed diabetes.
    found that the proportion of prediabetes in the elderly group was higher, but the proportion of people with normal blood sugar levels during follow-up was higher than that of those diagnosed with diabetes.
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