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JAMA Intern Med: Impact of SGLT-2 Inhibitors vs. Sulfonylureas on the Risk of Death in Patients with Type II Diabetes

 Last Update: 2021-07-31
 Source: Internet
 Author: User

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SGLT2 inhibitors are a new class of antihyperglycemic drugs mechanism, which reduces type II diabetes patients with poor cardiac vascular risk and renal events

Diabetes, heart blood vessels metformin Recently researchers compared the effects of SGLT2 inhibitors and sulfonylureas in patients with type II diabetes, all-cause mortality

This study used data from the US veterans database to investigate the use of SGLT2 inhibitors and sulfonylureas in patients with type II diabetes on the basis of metformin treatment

The average age of the participants was 64.

Compared with sulfonylurea drugs, the use of SGLT2 inhibitors is associated with a reduction in all-cause mortality of patients (hazard ratio [HR]=0.

Studies believe that compared with sulfonylureas, the use of metformin-SGLT-2 inhibitor combination therapy can reduce the risk of all-cause death in patients with type II diabetes

Compared with sulfonylureas, combined treatment with metformin-SGLT-2 inhibitors can reduce the risk of all-cause death in patients with type II diabetes.

Original source:

Yan Xie et al.

Comparative Effectiveness of Sodium-Glucose Cotransporter 2 Inhibitors vs Sulfonylureas in Patients With Type 2 Diabete.
JAMA

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