JAMA Netw Open: A cohort study of more than 1.1 million people shows that cesarean section can increase the risk of neurodevelopmental disorders in children, which may be related to family inheritance!

Neurodevelopmental disorders are a group of childhood diseases that usually last into adulthood.

Neurodevelopmental disorders are a group of childhood diseases that usually last into adulthood.

Recently, a study published in the journal JAMA Netw Open conducted a cohort study of more than 1.

Recently, a study published in the journal JAMA Netw Open JAMA conducted a cohort study of more than 1.

In this study, the researchers based cohort study of Swedish registration born in 1990 Nian 1 Yue 1 to 2003 Nian 12 Yue 31 between May 1179341 single full-term fetus, as well as their brothers and sisters, mothers and fathers Follow-ups of half-siblings and mother’s cousins ​​were conducted to explore the impact of cesarean section on children’s neurodevelopment and mental illness, as well as the relationship between children’s neurodevelopment and mental illness and familial confounding factors.

In this study, the researchers based cohort study of Swedish registration born in 1990 Nian 1 Yue 1 to 2003 Nian 12 Yue 31 between May 1179341 single full-term fetus, as well as their brothers and sisters, mothers and fathers Follow-ups of half-siblings and mother’s cousins ​​were conducted to explore the impact of cesarean section on children’s neurodevelopment and mental illness, as well as the relationship between children’s neurodevelopment and mental illness and familial confounding factors.

The study found that in 1,179,341 children, there are 1048838 of them have been vaginal delivery, accounting for boys 50.

After controlling for covariates (parental and neonatal characteristics, maternal comorbidities and pregnancy complications), compared with vaginal delivery, CD delivery can increase childhood neurodevelopmental disorders (plan CD , hazard ratio [HR] , 1.

After controlling for covariates (parental and neonatal characteristics, maternal comorbidities, and pregnancy complications) , CD CD delivery can increase childhood neurodevelopmental disorders compared with vaginal delivery, compared with vaginal delivery , and compared with vaginal delivery (plan childbirth can increase children's neurodevelopmental disorders childbirth can increase children's neurodevelopmental disorders CD , hazard ratio [HR] , 1.

 

The association between CD delivery and neurodevelopmental disorders may be explained by family factors, especially common maternal factors.

The association between CD delivery and neurodevelopmental disorders may be explained by family factors, especially common maternal factors.

In summary, compared with children born through vaginal delivery, children born with CD are diagnosed with neurodevelopmental disorders, and the risk of ADHD and mental retardation increases by 10 % to 30 %.

In summary, compared with children born via vaginal delivery, children born with CD are diagnosed with neurodevelopmental disorders, and the risk of ADHD and intellectual disability is increased by 10 % to 30 % .

Original source

Tianyang Zhang, MSc1,2,3;Gustaf Brander, PhD1,2,4 ;Ängla Mantel, MD, PhD5,6 ; et al.

Tianyang Zhang, MSc1,2,3;  Gustaf Brander, PhD1,2,4 ;  Ängla Mantel, MD, PhD5,6 ; et al.
com/journals/jamanetworkopen/fullarticle/2777034" target="_blank" rel="noopener">Assessment of Cesarean Delivery and Neurodevelopmental and Psychiatric Disorders in the Children of a Population-Based Swedish Birth Cohort .
JAMA Netw Open.
2021;4(3):e210837.
doi:10.
1001/jamanetworkopen.
2021.
0837 Gustaf Brander, PhD1,2,4 Ängla Mantel, MD, PhD5,6 com/journals/jamanetworkopen/fullarticle/2777034" target="_blank" rel="noopener">Assessment of Cesarean Delivery and Neurodevelopmental and Psychiatric Disorders in the Children of a Population-Based Swedish Birth Cohort.
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