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JAMA Netw Open: Can vaccines that have been validated in clinical trials apply to everyone?

 Last Update: 2021-03-20
 Source: Internet
 Author: User

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Vaccines are one of the most important public health developments in the last century.

Vaccines are one of the most important public health developments of the last century, greatly reducing the morbidity and mortality of major infectious diseases worldwide.

As we all know, the effectiveness and safety of vaccines must be verified by clinical trials from research and development to clinical application.

prevention

Flores et al.

Research Process

Main results and metrics: The number and percentage of races/minorities, women, and senior citizens compared to the 2011 and 2018 U.

Report on race/ethnicity test statistics

This analysis included 230 clinical trials with a total of 219 555 participants.

Each trial reported the age and gender of the subjects; 134 (58.

Compared with U.

Demographic characteristics of different trials

Adult trials consisted of more female participants (75?325[56.

The adult trial consisted of more female participants (75?325[56.

Among the trials that reported race/ethnicity, 65 (48.

In summary, this cross-sectional study found that in the US-based vaccine clinical trials, members of ethnic/minority groups and the elderly are under-represented, while female adults are over-represented.

Original source:

Flores Laura E, Frontera Walter R, Andrasik Michele P et al.

org/10.
1001/jamanetworkopen.
2020.
37640">The Racial of the Inclusion of Assessment / Ethnic Minority, for Woman, and the Individuals Older Vaccine Clinical Trials in JAMA in this message

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