JAMA Netw Open: Impact of lifestyle interventions on preventing worsening of glycemic status in South Asian women with gestational diabetes mellitus

Why it matters: Recent studies have shown that women with gestational diabetes mellitus (GDM) are at increased risk of developing type 2 diabetes

Design, settings, and participants: This randomized, participant open-label controlled trial investigated a 12-month life>

Main outcomes and methods of measurement: The primary outcome was the classification of glycemic exacerbation according to the American Diabetes Association criteria OGTT: (1) normal glucose tolerance to prediabetes (ie, impaired fasting glucose or impaired glucose tolerance) or type 2 diabetes or (2) diabetes mellitus Pre-to-type 2 diabetes

RESULTS: A total of 1823 women (baseline mean [SD] age 30.

Figure 1 Kaplan-Meier plot of the main results

Table 1 Effects of the intervention on secondary outcomes

Conclusions: This study found that a majority of women in urban South Asian settings developed dysglycemia shortly after a GDM-affected pregnancy, and that life>