JAMA Netw Open: Relationship between age and course of diabetes diagnosis in older adults and morbidity and mortality

Importance: Older adults vary greatly in the age of diagnosis and the duration of type 2 diabetes, but treatment often ignores this heterogeneity

ObjectiveTo investigate the relationship between

Design, Setup, and Participants: This cohort study included participants in the Health and Retirement Study (HRS) wave from 1995 to 2018, a population-based two-year longitudinal health interview survey

Exposure: The presence of diabetes, particularly at the age of diabetes diagnosis, was the main exposure

Key Results and Measurements: For each diabetes diagnostic age group, a control group with a preference score match was constructed consisting

Results: A total of 7739 HRS responders developed diabetes mellitus and were included in the analysis (4267 women [55.

Figure 1 Incidence of distal outcomes for each diabetes diagnostic age group and its matching control group (MC).

Figure 2 Cumulative incidence curve of distal results for each diabetes diagnostic age group and its matching control group (MC).

Figure 3 Diabetes Diagnosis by Age Group, Ratio of Harm to Distal Results (HR) of Diabetes Compared to Matched Control Groups (MCs)

Conclusions: The results of this cohort study suggest that there is a difference in age and prognosis for diabetes diagnosis, with a higher

Source: Cigolle CT, Blaum CS, Lyu C,et al.