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Among adults under the age of 50 in the United States, colorectal cancer (CRC) is the second most common cancer and the third leading cause of cancer death
.
Although there is no clear definition of early colorectal cancer, in the published literature, age less than 50 years seems to be a universal standard
.
Among adults under the age of 50 in the United States, colorectal cancer (CRC) is the second most common cancer and the third leading cause of cancer death
Early-onset CRC (that is , CRC diagnosed at the age of 50 ) has unique clinical, genetic and epigenetic characteristics.
Therefore, in individuals over 50 years of age, it may be related to the different survival rate of the diagnosed colon cancer
Early-onset CRC (that is , CRC diagnosed at the age of 50 ) has unique clinical, genetic and epigenetic characteristics.
In addition, patients with early-stage colorectal cancer are more likely to be diagnosed at an advanced stage
The patients included in this cohort study were 0-90 years old and were diagnosed with primary colorectal cancer from January 1, 2004 to December 31, 2015
.
The patients included in this cohort study were 0-90 years old and were diagnosed with primary colorectal cancer from January 1, 2004 to December 31, 2015
The results of the study showed that among the 769,871 patients with colorectal cancer (377,890 (49.
Age distribution of colorectal cancer patients diagnosed and staged in the National Cancer Database
Age distribution of colorectal cancer patients diagnosed and staged in the National Cancer Database Age distribution of colorectal cancer patients diagnosed and staged in the National Cancer Database Age distribution of colorectal cancer patients diagnosed and staged in the National Cancer DatabaseHowever, after adjusting for other factors related to mortality (most notably staging), patients with early-onset colorectal cancer have a lower risk of death compared with patients aged 51 to 55 years
.
However, after adjusting for other factors related to mortality (most notably staging), patients with early-onset colorectal cancer have a lower risk of death compared with patients aged 51 to 55 years
Comparison of the total mortality of early and late colorectal cancer
Comparison of the total mortality of early and late colorectal cancer.Comparison of the total mortality of early and late colorectal cancer.
This study found that in an unadjusted analysis, the mortality rate of younger CRC patients increased, which is related to being diagnosed in the later stages of the disease
.
This also shows that if more screening of younger patients allows their disease to be detected at an early stage, it may reduce their mortality
.
This study found that in an unadjusted analysis, the mortality rate of younger CRC patients increased, which is related to being diagnosed in the later stages of the disease
.
This also shows that if more screening of younger patients allows their disease to be detected at an early stage, it may reduce their mortality
.
This study found that in an unadjusted analysis, the mortality rate of younger CRC patients increased, which is related to being diagnosed in the later stages of the disease
.
This also shows that if more screening of younger patients allows their disease to be detected at an early stage, it may reduce their mortality
.
This also shows that if more screening of younger patients allows their disease to be detected at an early stage, it may reduce their mortality
.
This also shows that if more screening of younger patients allows their disease to be detected at an early stage, it may reduce their mortality
.
The survival advantage associated with early-onset CRC in young individuals should be interpreted with caution because this advantage is small in scale and heterogeneous with age and stage
.
Further research is needed to understand the potential heterogeneity of survival at different ages and stages in patients with early colorectal cancer
.
.
Further research is needed to understand the potential heterogeneity of survival at different ages and stages in patients with early colorectal cancer
.
The survival advantage associated with early-onset CRC in young individuals should be interpreted with caution because this advantage is small in scale and heterogeneous with age and stage
.
Further research is needed to understand the potential heterogeneity of survival at different ages and stages in patients with early colorectal cancer
.
The survival advantage associated with early-onset CRC in young individuals should be interpreted with caution because this advantage is small in scale and heterogeneous with age and stage
.
Further research is needed to understand the potential heterogeneity of survival at different ages and stages in patients with early colorectal cancer
.
Further research is needed to understand the potential heterogeneity of survival at different ages and stages in patients with early colorectal cancer
.
Further research is needed to understand the potential heterogeneity of survival at different ages and stages in patients with early colorectal cancer
.
References: Cheng E, Blackburn HN, Ng K, et al.
Analysis of Survival Among Adults With Early-Onset Colorectal Cancer in the National Cancer Database.
JAMA Netw Open.
2021;4(6):e2112539.
doi:10.
1001/jamanetworkopen .
2021.
12539
Analysis of Survival Among Adults With Early-Onset Colorectal Cancer in the National Cancer Database.
JAMA Netw Open.
2021;4(6):e2112539.
doi:10.
1001/jamanetworkopen .
2021.
12539 References: Cheng E, Blackburn HN, Ng K, et al.
Analysis of Survival Among Adults With Early-Onset Colorectal Cancer in the National Cancer Database.
JAMA Netw Open.
2021;4(6):e2112539.
doi:10.
1001 /jamanetworkopen.
2021.
12539 References: Cheng E, Blackburn HN, Ng K, et al.
Analysis of Survival Among Adults With Early-Onset Colorectal Cancer in the National Cancer Database.
JAMA Netw Open.
2021;4(6):e2112539.
doi :10.
1001/jamanetworkopen.
2021.
12539Cheng E, Blackburn HN, Ng K, et al.
Analysis of Survival Among Adults With Early-Onset Colorectal Cancer in the National Cancer Database.
JAMA Netw Open.
2021;4(6):e2112539.
doi:10.
1001/jamanetworkopen.
2021.
12539 doi :10.
1001/jamanetworkopen.
2021.
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