JAMA Network Open: Pregnant mothers should not drink alcohol, it will affect their children

Nearly 10 percent of pregnant women drink alcohol, and alcohol can adversely affect fetal development and cause various physical, behavioral, and neurological deficits

Nearly 10 percent of pregnant women drink alcohol, and alcohol can adversely affect fetal development and cause various physical, behavioral, and neurological deficits

High levels of prenatal alcohol exposure (PAE) are associated with a wide range of behavioral and cognitive problems and altered brain structure

Xiangyu Long of the University of Caliga, Canada, published a research article entitled Evaluation of Brain Alterations and Behavior in Children With Low Levels of Prenatal Alcohol Exposure in JAMA Network Open, comparing children with low levels of PAE and well-matched children without PAE.

This cross-sectional study compared children with PAE to a control group matched for age, sex, household income, maternal education level, and caregiver status

This cross-sectional study compared children with PAE to a control group matched for age, sex, household income, maternal education level, and caregiver status

A total of 270 children were included in the analysis (mean [SD] age, 9.

Fractional anisotropy (FA) in white matter areas was lower in prenatal alcohol exposure (PAE) groups compared to unexposed controls

Fractional anisotropy (FA) in white matter areas was lower in prenatal alcohol exposure (PAE) groups compared to unexposed controls

Compared with controls, children with PAE had left retrocentral gyrus (0.

Compared with controls, children with PAE had left retrocentral gyrus (0.

Children with PAE had higher (worse) scores on externalizing behavior than controls (mean [SD], 45.

Partial anisotropy (FA) of white matter areas with significant subgroup differences correlated with Child Behavior Scale (CBCL) scores

Partial anisotropy (FA) of white matter areas with significant subgroup differences correlated with Child Behavior Scale (CBCL) scores

The study found that children with lower levels of PAE had lower levels of FA and more behavioral problems than well-matched controls .

The study found that children with lower PAE PAE levels had lower FA levels and more behavioral problems than

original source

Long X, Lebel C.

Long X, Lebel C.
Evaluation of Brain Alterations and Behavior in Children With Low Levels of Prenatal Alcohol Exposure.
JAMA Netw Open.
2022;5(4):e225972.
doi:10.
1001/jamanetworkopen.
2022.
5972 Long X, Lebel C.
Evaluation of Brain Alterations and Behavior in Children With Low Levels of Prenatal Alcohol Exposure.
JAMA Netw Open.
2022;5(4):e225972.
doi:10.
1001/jamanetworkopen.
2022.
5972 JAMA Netw Open.


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