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    Home > Active Ingredient News > Study of Nervous System > JAMA Neurol: The rate of different seizure cycles of eclampsia

    JAMA Neurol: The rate of different seizure cycles of eclampsia

    • Last Update: 2021-02-24
    • Source: Internet
    • Author: User
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    Epilepsy is characterized by periodic seizures, some people may have seizures once a year, some people may have seizures once a month, and others may have seizures once a day.
    , however, there is no clear data on how many people have seizures once a year, how many people have seizures once a month, and how many people have seizures once a day.
    , Leguia and others conducted a retrospective queue study aimed at identifying the prevalence, intensity and time patterns of epilepsy in different seizure cycles (hours to years).
    selected 222 adult patients with resuscticative eclampsia from 256 participants in a clinical trial of an implantable reactive nerve stimulation device and analyzed persistent intracranial electrocultural maps (cEEG) and epilepsy records collected between January 19, 2004 and May 18, 2018 for a period of 10 years.
    main evaluation indicators include: (1) self-reported daily seizure count, (2) cEEG-based hourly seizure count, (3) interstational epilepsy-like activity (IEA) detection.
    of the 222 subjects, 112 (50 per cent) were male and the middle age was 35 (18-66). The
    attack cycle (approximately 1 year) was 12% (24/194), the multiple seizure cycle (approximately weekly to one month) was 60% (112/186) and the circadian attack cycle (approximately 24 hours) was 89% (76/85).
    the intensity of seizures during the day, night and multiple cycles is comparable, while the intensity of seizures in the annual cycle is weak.
    who have a circadian seizure cycle have five peak seizures: morning, 3 p.m., evening, evening, and late at night.
    IEA peak cycle is mostly around 7, 15, 20, 30 days.
    large-scale queue study revealed the occurrence of recurrent epilepsy in different seizure cycles, helping to explain the natural variability of seizure time.
    results may provide information for the schedule of diagnostic studies, time-varying therapies, and the design of epilepsy-related clinical trials.
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