echemi logo
Product
  • Product
  • Supplier
  • Inquiry
    Home > Active Ingredient News > Antitumor Therapy > JAMA Oncology: All-trans retinoic acid combined with arsenic trioxide has a significant effect on childhood leukemia

    JAMA Oncology: All-trans retinoic acid combined with arsenic trioxide has a significant effect on childhood leukemia

    • Last Update: 2021-12-04
    • Source: Internet
    • Author: User
    Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

    A phase III clinical trial conducted by the Childhood Oncology Group showed that a combination of drugs is very effective for children with standard and high-risk acute promyelocytic leukemia (also known as APL)


    child

    Acute promyelocytic leukemia is a subtype of acute myeloid leukemia


    APL is an acute leukemia, which means it develops rapidly and requires immediate treatment


    diagnosis

    The results of the trial were published in JAMA Oncology on November 11.


    JAMA

    In the trial, 154 children between the ages of 1 and 22 with a new diagnosis of standard or high-risk APL received oral all-trans retinoic acid and intravenous arsenic trioxide for at least 28 days


    The two-year overall survival rates for children with standard and high-risk APL are 99% and 100%, respectively, and the event-free survival rates are 98% and 96%, respectively


    Original source:

    Original source:

    https:// href="https://" target="_blank" rel="noopener">https:// https://


    This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

    Contact Us

    The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

    Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.