JAMA Oncology: Can aspirin reduce the risk of colorectal cancer in older adults? It depends on when they start taking the medicine

Regular use of aspirin has significant benefits in reducing the incidence of colorectal cancer in middle-age adults, but there are also risks, such as gastrointestinal bleeding.
should adults start taking aspirin regularly, for how long? There is ample evidence that taking aspirin daily can reduce the risk of colorectal cancer in adults under the age of 70.
but until now, there has been no evidence that older people should start taking aspirin.
study, led by Andrew T. Chan of Massachusetts General Hospital (MGH), was published in JAMA Oncology.
researchers conducted a summary analysis of two large U.S. queue studies that provided data on the use of aspirin by about 35,500 participants over the past 35 years, providing a unique opportunity to understand the impact of aspirin on cancer risk.
found that routine use of aspirin was associated with a reduced risk of colorectal cancer.
, this advantage only makes sense for people who start taking aspirin before the age of 70.
people who started using aspirin regularly in their 70s or older don't seem to have any benefit.
Related Research: Gastroenterology: Specific Enterobacteria Degrades Aspirin, Reduces aspirin's Effectiveness in Preventing Colorectal Cancer JGH OPEN: Aspirin's Impact on the Occurrence and Survival of Gastric Cancer JAMA Oncology: Start using Aspirin at a young age, and the risk of colorectal cancer is significantly reduced! JAMA Netw Open: Evaluation of aspirin use and cancer incidence and survival rates in elderly patients NEJM: 50,000 studies have shown that "God's drug" aspirin may prevent liver cancer Lancet: The Lancet new article consolidates aspirin's "God medicine" status, taking the drug for two years can reduce the risk of colorectal cancer in high-risk groups Lancet Gastron Hepatol: A The safety assessment of Spirin tumor-assisted therapy Clin Gastroenterology H: Single-use or combined clopidogrel and low-dose aspirin can reduce the risk of colorectal cancer PNAS: Aspirin stimulates the withdrawal of cancer JGH: Low-dose aspirin can reduce the mortality rate of post-surgery colorectal cancer JAMA Intern Med: aspirin or liver cancer prevention! Analysis Chinese 15 years of data found that long-term use of aspirin was associated with a 29% reduction in liver cancer risk in patients with chronic hepatitis B