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Marijuana is a commonly used psychotropic drug, especially among adolescents and young people in the United States
Marijuana is a commonly used psychotropic drug, especially among adolescents and young people in the United States
The neurobiological mechanisms that may mediate the long-term behavioral association with cannabis use remain unclear
The neurobiological mechanisms that may mediate the long-term behavioral association with cannabis use remain unclear
Based on these, a research team analyzed the correlation between the development of cerebral cortex thickness assessed by magnetic resonance (MR) imaging and cannabis use in longitudinal samples of adolescents
The data comes from a community-based IMAGEN cohort study conducted at 8 European sites
The data comes from a community-based IMAGEN cohort study conducted at 8 European sites
According to the European School Alcohol and Other Drug Survey Project, a baseline assessment of cannabis use and a 5-year follow-up were conducted
The study evaluated 1598 MR images of 799 participants (450 female participants [56.
Longitudinal analysis shows that age-related cortical thinning is limited by cannabis use in a dose-dependent manner, so from baseline to follow-up, more cannabis use is associated with increased left and right prefrontal cortex thinning
In this sample, the spatial pattern of cannabis-related thinning was related to age-related thinning, and positron emission tomography assessed the cannabinoid 1 receptor binding profile from a sample of individual participants
Magnetic Resonance Imaging-Assessing varying degrees of cortical thinning with lifetime cannabis use
Magnetic Resonance Imaging-Evaluation of different degrees of cortical thinning in lifetime use of marijuana MRI-Evaluation of different degrees of cortical thinning in lifetime use of marijuana MRI-Evaluation of different degrees of cortical thinning in lifetime use of marijuanaIn summary, the results indicate that the use of cannabis in mid-to-late adolescence may be related to changes in cortical development, especially in the prefrontal areas that are rich in CB1 receptors and exhibit long-term maturation trajectories
In summary, the results indicate that the use of cannabis in mid-to-late adolescence may be related to changes in cortical development, especially in the prefrontal areas that are rich in CB1 receptors and exhibit long-term maturation trajectories
The researchers reported evidence of an association between juvenile cannabis use and developmental changes in cortical thickness in a longitudinal sample of adolescents
References: Albaugh MD, Ottino-Gonzalez J, Sidwell A, et al.
Association of Cannabis Use During Adolescence With Neurodevelopment.
JAMA Psychiatry.
Published online June 16, 2021.
doi:10.
1001/jamapsychiatry.
2021.
1258 References: Albaugh MD, Ottino -Gonzalez J, Sidwell A, et al.
Association of Cannabis Use During Adolescence With Neurodevelopment.
JAMA Psychiatry.
Published online June 16, 2021.
doi:10.
1001/jamapsychiatry.
2021.
1258 Albaugh MD, Ottino-Gonzalez J, Sidwell A, et al.
Association of Cannabis Use During Adolescence With Neurodevelopment.
JAMA Psychiatry.
Published online June 16, 2021.
doi:10.
1001/jamapsychiatry.
2021.
1258 doi:10.
1001/jamapsychiatry.
2021.
1258
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