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    Home > Active Ingredient News > Study of Nervous System > JAMA: Study of long-term stroke risk after a short-term isoemia attack

    JAMA: Study of long-term stroke risk after a short-term isoemia attack

    • Last Update: 2021-03-03
    • Source: Internet
    • Author: User
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    Short-term cerebral ischemic attack (TIA), commonly known as "stroke", refers to a short-term neurofunctional defect attack caused by ischemic ischemic infarction of the brain or retinal bureau.
    clinical symptoms generally recover within 1-2 hours, no remnants of neurofunction symptoms and signs, and there is no evidence of acute cerebral infarction in imaging.
    TIA is an important precursor to stroke, and raising awareness, identifying high-risk people and managing them in a timely manner can greatly reduce the risk of stroke in high-risk groups.
    recently looked at long-term trends in the incidence of TIA in the population and the risk of stroke after TIA.
    The study was a retrospective cohort study of the Framingham Heart Research Cohort, which collected data from 14,059 participants who had no TIA or stroke history at the baseline check-up, and compared patients with first-time TIA seizures during follow-up with participants without TIA seizures, with age and gender comparability among the groups. the main endpoints of the
    study were TIA incidence in the general population, the incidence of short-term strokes (7 days, 30 days and 90 days) after the first TIA, and the incidence of long-term stroke (greater than 1-10 years), compared to stroke patients without TIA history. The risk of stroke in the population, as well as the trend of changes in stroke risk in the 90 days after TIA over three periods (1954-1985, 1986-1999 and 2000-2017).
    During the 66-year follow-up period, 435 out of 14,059 participants experienced TIA seizures (229 women; average age of seizures was 73.47 years; 206 men, average age of seizures 70.10 years), the incidence rate of TIA was estimated at 1.19 per 1000 years.
    130 participants (29.5%) had a stroke in the 8.86 years after TIA: 28 had a stroke within 7 days of TIA (21.5%) and 40 (3) 0.8%) occurred within 30 days, 51 (39.2%) within 90 days, 63 (48.5%) within 1 year and above after TIA, and the average stroke time was 1.64 years after TIA.
    After age and gender adjustment, the cumulative risk of stroke in TIA patients (130 strokes out of 435) was 0.46 within 10 years, while the matching control group without TIA (165 strokes out of 2175) was 0.09 and the adjusted risk ratio was 4.37.
    found that between 1948 and 1985, the risk of stroke in the 90 days after TIA was 16.7% (26 strokes out of 155 TIA patients), 1986-1999 This decreased to 11.1% (18 strokes out of 162 patients), while the risk fell further to 5.9% in 2000-2017 (7 strokes out of 118 patients).
    1986-1999 and 2000-2017 TIA patients had a 90-day stroke risk of 0.60 and 0.32, respectively, compared with 1948-1985.
    stroke risk increased fourfold after a short-lived isoemia attack, and in recent years the risk of stroke in patients has decreased by nearly 70% in the 90 days after TIA as post-TIA care has increased.
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