With the improvement of living standards, "big fish meat" has become a regular on people's daily table, with the attendant high uric acidemia and gout has become one of the most common metabolic diseases.
, gout is a metabolic arthritis caused by the deposition of high uric acid in the joints, causing inflammation and pain in the joints, and is often "painful" when it strikes, so gout is also considered one of the most painful diseases.
that since gout attacks are so painful, scientists have been looking for ways to prevent high uric acidemia and even gout.
, a team of experts from Harvard Medical School recently published their findings in jama's sub-journal, JAMA Network Open.
researchers used data from the U.S. Health Professional Follow-up Study (HPFS), which included 51,529 male health workers.
follow-up of this group from 1986 to 2012, with a follow-up survey of individuals' physical condition every 2 years.
follow-up, a total of 44,654 participants without underlying ginges were analyzed.
based on the aggregated questionnaire, the participants were strated according to the following factors: normal body mass index (BMI<25), alcohol consumption, adherence to DASH diet patterns, and use of diuretics.
DASH diet is a balanced diet that emphasizes fruits, nuts and dairy products, promotes a reduction in the intake of high-sugar foods, beverages, and red meat (such as beef and mutton), and replaces saturated fatty acids with high potassium, magnesium, high calcium, dietary fiber and unsaturated fatty acids to lower blood pressure and protect arteriosclerosis.
1,741 (3.9%) of participants had gout seizures after an average of 26 years of follow-up.
all participants, the above four risk factors were able to prevent 77% (95% CI, 56-88%) of gout attacks! Body mass index (BST) is the most important factor.
BMI ≤ 23.0 (normal upper limit), 25.0-29.9 (overweight) and ≥30.0 (obese) participants had a 29 percent, 90 percent and 165 percent increased risk of gingwind compared to people with a BMI of 23.0≤23.0.
body mass index, the other three factors were also associated with the risk of gout attacks.
, for example, can prevent 22% of gash if you follow the DASH diet pattern.
risk of gyration was more than halved compared to those who consumed more than 30g of alcohol a day.
, not using diuretics can cut the risk of gyration in half.
risk of gyringe occurring by combination of different risk factors.
further analysis found that maintaining weight (BMI<25), coupled with non-drinking or DASH eating habits, prevented 43 percent and 33 percent of the risk of gingwinds, respectively.
if these three can be done, 69% of cases can be prevented.
, the risk of gyr ≥ did not decrease even among obese (BMI≥30) men.
, maintaining a normal weight is a prerequisite for other factors to play a protective role.
"This study quantifies the effects of obesity on gage," said study co-author Dr. Hyon K. Choi of the Rheumatology Immunology Department at Harvard Medical School in Massachusetts.
, the study demonstrated the role of lifestyle interventions in gyringe prevention, noting in particular the importance of maintaining weight.
: McCormick N, Rai SK, Lu N, et al. Estimation of Primary Prevention of Gout in Men Through Modification of Obesity and Other Key Lifestyle Factors. JAMA Netw Open. 2020 Nov 2; 3(11):e2027421. doi: 10.1001/jamanetworkopen.2020.27421.MedSci Original Source: MedSci Original Copyright Notice: All noted on this website "Source: Met Medical Or "Source: MedSci Original" text, images and audio-visual materials, copyrights are owned by Metz Medicine, without authorization, no media, website or individual may reproduce, authorized to reproduce with the words "Source: Mets Medicine".
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