JAMA Surg: 2014 SSO-ASTRO New guidelines for breast cancer breast surgery cut-out reduce the risk of re-surgery in patients.

In 2014, the American Society of Surgical Oncology (SSO) and the American Society of Radiological Oncology (ASTRO) jointly developed new guidelines for breast cancer surgical cut-off, proposing the concept of a 'negative cut-off', a tumor-free area of the specimen, with the aim of reducing the rate of re-surgery in patients with early breast cancer who undergo mastectomy.
recently examined changes in surgical rates following the release of the SSO-ASTRO guidelines.
This study is a systematic review and meta-study, collecting relevant studies from January 2014 to July 2019, with a total of 30 studies involving 599,016 participants, 20 of whom were conducted in the United States, 6 in the United Kingdom, 3 in Canada and 1 in Australia.
in 21 studies of actual changes in reseeding rates, the rate of reseedation in patients decreased statistically after the publication of the guidelines (OR=0.62).
in nine trend prediction studies, the rate of re-surgery after the implementation of the 1mm edge threshold was significantly reduced compared to the edge threshold of 2 mm or more in the original guidelines (OR=0.47).
study, which assessed the economic benefits of costs, found that under the new guidelines, an average of $3,540 in medical expenses would be saved for every female patient who avoided re-surgery.
study concluded that the rate of re-surgery in patients with early breast cancer decreased following the release of new guidelines for breast cancer preservation surgery in 2014.
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