Japanese research team will treat cancer with iPS cells

According to foreign media, the Japanese research team will use induced pluripotent stem cells to treat cancer According to the Japanese Yomiuri Shimbun on January 10, the research team of the Institute of science and chemistry and Chiba University plans to start clinical trials within this year (http://www.chemdrug.com/sell/24/), using human induced pluripotent stem cells (iPS cells) to make special immune cells, and then supply them to patients with head and neck cancer The treatment attempts to shrink cancer cells by boosting immunity The clinical trials of iPS cells in the treatment of cancer are the first in Japan The research team led by Gu guanmingyan, deputy director of life medical science research center of Institute of science and chemistry, and Okamoto Meixiao, Professor of Chiba University are planning to carry out clinical trials According to the plan, a kind of immune cell named "NKT cell" will be made from iPS cells of healthy (http://www.chemdrug.com/article/7/) people, and then injected into the blood vessels connecting cancer patients The subjects of the clinical trial were 3 recurrent patients who were difficult to operate At first, 30 million immune cells were injected, and then the side effects were observed while adjusting the number of cells, which were provided in three times Researchers plan to spend two years investigating the safety and efficacy of the treatment Researchers such as Gu guanmingyan began to focus on the unlimited increase of iPS cells They developed a way to extract NKT cells from human blood, first make them into iPS cells for proliferation, and then into NKT cells again After the cells were provided to mice, it was found that they could inhibit the proliferation of cancer cells If this clinical trial confirms that there is no problem with safety, the next step will be to investigate the effectiveness of clinical trials This treatment may also be applied to the treatment of lung cancer.