JASN: Relationship between AKI and CKD in people with type 2 diabetes.

Few observational studies assessed the risk of AKI in people with type 2 diabetes, while fewer studies looked at the relationship between AKI and CKD in that population.
compared to non-diabetic populations, this limits understanding of the interaction between AKI and CKD in people with type 2 diabetes.
In a recent study published in Journal, an authoritative journal in the field of kidney disease, researchers analyzed participants with or without type 2 diabetes and used electronic medical records to assess the incidence of AKI, using a variety of statistical methods to determine their relationship to CKD status and further decline in kidney function.
followed 16,700 participants (9,417 with type 2 diabetes and 7,283 without diabetes control), with a median age of 8.2 years.
people with diabetes were more likely to have AKI (48.6% and 17.2%, respectively) and had CKD or CKD progression prior to follow-up (46.3% and 17.2%, respectively).
in the absence of CKD, the incidence of AKI in diabetics was almost five times that of the control population (121.5 vs. 24.6 per 1,000 people per year).
Among participants with CKD, the incidence of AKI in diabetics was more than twice that of the controls (384.8 vs. 180.0 per 1,000 people per year after CKD diagnosis, compared with 109.3. vs. 47.4 per 1,000 CKD patients after recruitment).
, the decline in eGFR slope was steeper in diabetics before AKI became ill than in the controls.
, the eGFR slope of patients without diabetes decreased more severely after AKI became ill, but not in patients with diabetes and CKD.
result, the incidence of AKI in diabetics increased significantly compared to those without diabetes, and this is still the case in patients with CKD.
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