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    Home > Active Ingredient News > Endocrine System > JBMR: Cognitive decline is associated with accelerated bone loss and increased fracture risk in women

    JBMR: Cognitive decline is associated with accelerated bone loss and increased fracture risk in women

    • Last Update: 2021-11-03
    • Source: Internet
    • Author: User
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    Purpose: Cognitive decline and osteoporosis often coexist, and some evidence suggests that there is a causal relationship between the two


    Cognitive decline and osteoporosis often coexist, and some evidence suggests that there is a causal relationship between the two


    Results: More than 95% of participants had normal cognition at baseline (MMSE≥24)


    Table 1 Predictors of female bone loss derived from linear mixed-effects model

    Table 1 Predictors of female bone loss derived from linear mixed-effects model

    Table 2 The risk of fracture in women with cognitive decline (5-15 years) compared with women without cognitive decline (0 years and 5 years)

    Table 2 The risk of fracture in women with cognitive decline (5-15 years) compared with women without cognitive decline (0 years and 5 years)

    The graph shows the unadjusted and multivariately adjusted Kaplan-Meier fracture probability curve (0 and 5 years) of women with cognitive decline compared with women without cognitive decline


    The graph shows the unadjusted and multivariately adjusted Kaplan-Meier fracture probability curve (0 and 5 years) of women with cognitive decline compared with women without cognitive decline


    In women, cognitive decline is significantly associated with bone loss and fracture risk, regardless of age


    Bliuc D, Tran T, Adachi JD,et al.


    Cognitive decline is associated with an accelerated rate of bone loss and increased fracture risk in women: a prospective study from the Canadian Multicentre Osteoporosis Study.


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