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    Home > Active Ingredient News > Endocrine System > JBMR: Vitamin D metabolism rate is related to changes in bone mineral density and fracture risk in the elderly

    JBMR: Vitamin D metabolism rate is related to changes in bone mineral density and fracture risk in the elderly

    • Last Update: 2021-11-03
    • Source: Internet
    • Author: User
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    BACKGROUND AND OBJECTIVE: Recent studies have shown that 25-hydroxyvitamin D (25 (OH) D) may not be prompted to bone health biomarkers, due in part to measure the level of protein binding and contains both free vitamin D


    Recent studies have shown that 25-hydroxyvitamin D (25 (OH) D) may not be prompted to bone health biomarkers, due in part to measure the level of protein binding and contains both free vitamin D


    The average age of these participants was 75 ± 3 years, 49% were women, 42% were black, and 23% had an estimated glomerular filtration rate (eGFR) <60 mL/mL/1.


    Table 1 The relationship between vitamin D metabolites and VMR in 753 healthy ABC cohort participants and the annual percentage change of total hip BMD

    Table 1 The relationship between vitamin D metabolites and VMR in 753 healthy ABC cohort participants and the annual percentage change of total hip BMD

    Table 2 The relationship between vitamin D metabolites and VMR and fracture risk in 788 healthy ABC cohort participants

    Table 2 The relationship between vitamin D metabolites and VMR and fracture risk in 788 healthy ABC cohort participants

    The graph depicts the spline function of the relationship between vitamin D metabolites and VMR and fracture risk


    The graph depicts the spline function of the relationship between vitamin D metabolites and VMR and fracture risk


    In a cohort of elderly people living in a diverse community, lower VMR was more closely related to bone density loss and fracture risk than 25(OH)D3


    Ginsberg C, Hoofnagle AN, Katz R,et al.


    The Vitamin D Metabolite Ratio is Associated with Changes in Bone Density and Fracture Risk in Older Adults

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