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Osteoporosis affects about 15% of patients with inflammatory bowel disease (IBD), but the disease occurs in a different way than the general population.
in the general population, osteoporosis usually occurs in thin, post-menopapaan women, family history, smoking status and alcohol consumption usually play a role.
but in people with BD, men and women have a similar risk of osteoporosis and age plays a big role, and hormone use appears to be a driver of the disease's development.
previous study of fractures in IBD patients found that the risk was "40 per cent higher than in the general population".
under 40, the risk of fractures is 37 percent higher than in the general population, and the risk increases with age.
a recent study that conducted a 10-year-long queue study further confirmed the findings.
Recently, Danish researchers, to investigate the incidence of osteoporosis in IBD patients, specifically followed up with patients with CD and UC who were in the group between 2003 and 2004 until 2015, using relevant statistical models to calculate the incidence of osteoporosis.
a total of 513 patients were included in the study, including 213 CD patients and 300 UC patients, according to the study, which was conducted at doi.org/10.1093/ecco-jcc/jjaa019.
overall, 338 patients (CD:164 (77 percent), UC:174 (58 percent), p.lt;001) were treated with corticosteroids of up to 500 mg in one year, resulting in a total of 781 patients with osteoporosis.
during the follow-up period, a total of 73 patients with IBD (CD:31 (14.6 per cent), UC:42 (14 per cent)) and 680 (6.6 per cent), p.lt;0.001) were diagnosed with osteoporosis.
risk of osteoporosis increased compared to the control group (OR:CD:2.9 (95% confidence interval: 2.0-4.1) and UC:2.8 (2.1-3.9)).
study confirmed that the risk of osteoporosis in patients with inflammatory bowel disease was significantly higher than in the control group.
, tell us that clinicians need to learn more about the risk of osteoporosis in IBD patients.
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