JCEM: Association between exposure to air pollution in adults and thyroid function
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Last Update: 2020-06-25
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Source: Internet
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Author: User
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Although there is a significant link between air pollution and thyroid function in a limited sample or area, few studies have explored this link in the general population, in a recent study published in journal Anda eicrinology and Clinical Endocrinology and Metabolism, researchers used a national sample of Korean adults to investigate the association between air pollution exposure and thyroid function, and further analyze whether this association differs in subgroups by age or body mass index (BMI)In the final analysis, the researchers included 4,704 adults and analyzed the average annual exposure of each of the four air pollutants, namely, particulate matter (PM10), nitrogen dioxide (NO2), sulfur dioxide and carbon monoxide (CO) with an aerodynamic diameter of 10 mThe researchers measured serum thyroid-stimulating hormone (TSH) and free thyroxine (FT4) concentrations based on age and BMI, and used them as indicators of thyroid functionadjust possible confounding factors, the average annual exposure to NO2 and CO was significantly correlated with elevated TSH and reduced FT4 concentration (all p 0.05)In men, PM10 exposure was positively correlated with TSH levels except for these two pollutants (p.03)Age stratification analysis showed that NO2 and CO exposure in older people had a greater impact than in younger peopleExposure to these air pollutants was associated with serum TSH and FT4 concentrations in overweight or obese populations, and not to normal-weight populationsthe evidence provided by the study that air pollution exposure is associated with thyroid function in the general population, and that the association is stronger in older, overweight or obese adults
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