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JCEM: Association between long-term weight change and dementia in later life

 Last Update: 2022-05-13
 Source: Internet
 Author: User

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Dementia is a major neurodegenerative disease that threatens the healthy lifespan of older adults and imposes an enormous medical burden on health systems around the world

prevention

A study published in the Journal of Clinical Endocrinology & Metabolism, an authoritative journal in the field of endocrine and metabolic diseases, aimed to investigate the long-term and temporal relationship between weight change and dementia risk in middle-aged and older adults in the United States

The study consisted of 5,985 participants aged 50 and older, all from the Health and Retirement Research (HRS)

During the study follow-up period (mean 7.

Statistical diagnosis

It can be seen that both short-term and long-term weight loss are associated with a higher risk of Alzheimer's disease in middle-aged and elderly people, which is not related to physical frailty

Both short-term and long-term weight loss were associated with a higher risk of Alzheimer's disease in middle-aged and older adults, independent of physical frailty

Original source:

Jie Shen, et al.

Long-term weight change and its temporal relation to later-life dementia in the Health and Retirement Study

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