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Although the association between thyroid markers and gestational diabetes mellitus (GDM) has been extensively studied, the results are inconclusive and the mechanism is not yet clear
.
Recently, a research article was published in the Journal of Clinical Endocrinology & Metabolism, an authoritative journal in the field of endocrine and metabolic diseases.
Researchers aimed to investigate the prospective association between thyroid markers in early pregnancy and the risk of GDM
The study included 6,068 pregnant women from the Tongji-Shuangliu birth cohort
.
15 weeks ago, the maternal serum thyroid markers (free triiodothyronine (fT3), free thyroxine (fT4), thyroid stimulating hormone, thyroid peroxidase antibody and thyroglobulin antibody) were measured
The average age of the participants was 26.
6±3.
7 years, and the average gestational age was 10.
Lower serum fT4 concentration or higher fT3/fT4 ratio in early pregnancy is associated with an increased risk of GDM
Original source:
Yi Wang.
et al.
A prospective study of early-pregnancy thyroid markers, lipid species, and risk of gestational diabetes mellitus .
JCEM.
2021.
https://doi.
A prospective study of early-pregnancy thyroid markers, lipid species, and risk of gestational diabetes mellitus in this message