JCEM: Bone metabolism in adolescents undergoing bariatric surgery

Over the past few decades, the prevalence of childhood obesity has increased, along with metabolic and bariatric surgery (MBS).
although adult MBS is associated with bone loss, only a few studies have assessed the effects of MBS on bone growth in adolescents.
, a small review of the effects of the most commonly used MBS (sleeve gastric excision and gastric bypass) on adolescent bones was published in a recent study published in Journal of Clinical Endocrinology and Metabolism, an authoritative journal in the field of endocrinology and metabolic diseases.
researchers used PubMed to systematically search and review English literature.
all MBS, the regional bone mineral density (aBMD) and BMD Z scores measured by DXA were reduced.
year after the sleeve gastric excision, the mass BMD (vBMD) measured by the lumbar quantitative CT (QCT) decreased, while the cortital vBMD of the tibia and tibia increased (total vBMD unchanged).
period, the cross-sectional area between the narrow neck and roon and the thickness of the cortique were observed to decrease, and the estimation of hip strength was adversely affected.
year after a sleeve gastric excision, the bone marrow adipose tissue (MAT) in the lumbar spine increases, while the MAT in the exoskeleton is reduced.
weight loss, lean meat and fat loss were associated with bone loss in all areas and changes in bone microstructage in the surrounding areas.
result, adolescent MBS was associated with aBMD reduction and an increase in MATT in axial bones, while a sleeve gastric excision was associated with an increase in cortique vBMD and a decrease in MAT in surrounding bones.