JCEM: Can vitamin D supplementation prevent type 2 diabetes?

Vitamin D has been a determinant of the risk of type 2 diabetes over the past decade, and vitamin D supplementation is considered a potential intervention to reduce the risk of diabetes.
recently, some trials have reported the effects of vitamin D supplementation on the prevention of diabetes in prediabetes patients.
recently, Journal of Clinical Endocrinology, an authoritative journal in the field of endocrine and metabolic diseases. In a research paper published in Metabolism, researchers searched the PubMed, Embase, and ClinicalTrials.gov databases and conducted a comprehensive literature review to determine: 1) Recent Meta analysis based on longitudinal observation studies that reported a correlation between blood vitamin D (OH)D) levels and diabetes, and 2) reported on the effects of vitamin D supplementation on the development of diabetes in prediabetes adults.
longitudinal observational study reported a highly consistent association between higher blood 25 (OH) D levels and lower diabetes risk in different populations, including those with prediabetes.
trials of prediabetes patients have found that vitamin D supplementation reduces the risk of new diabetes.
three large trials designed to prevent diabetes, vitamin D supplementation reduced the risk of developing diabetes in people with prediabetes by 10 to 13 percent compared to placebo.
results are consistent with a wealth of evidence from observational studies showing that vitamin D plays an important role in regulating diabetes risk.
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