JCEM: Effect stake in vitamin D on diabetes incidence
-
Last Update: 2020-06-25
-
Source: Internet
-
Author: User
Search more information of high quality chemicals, good prices and reliable suppliers, visit
www.echemi.com
The effect of vitamin D supplementation on the risk of type 2 diabetes (T2DM) remains controversial because most randomized controlled trials (RCTs) are smaller or report only the effects of low-dose vitamin DIn a recent study published in journal Journal of Endocrine and Metabolic Diseases, researchers conducted a meta-analysis of RCT and assessed the role of vitamin D supplements in the prevention of T2DMtwo researcherssearched the databases of Pubmed, MEDLINE, EMBASE and cochrane libraries from the database to September 15, 2019The RCT, which the researchers included, reported on the effects of vitamin D supplementation on the prevention of T2DM for at least a yearTwo independent researchers extracted the data and reported risk ratios (RRs) and 95% confidence intervals (CIs)The main outcome of the meta-analysis was the incidence of T2DMthe analysis included nine RCTs (43,559 participants)The average age (SD) is 63.5 (6.7) yearsCompared to placebo, the RR of vitamin D was 0.96 (95% CI was 0.90-1.03); In the medium to high dose (1000IU/d) trials, all trials were conducted in prediabetes subjects, with a RR of 0.88 (95% CI was 0.79-0.99) compared to placebosConversely, low-dose tests in the sample of the general population did not show a reduction in risk (RR 1.02 (95% CI is 0.94-1.10);in prediabetes patients, moderate to high doses (1000 IU/d) instead of low doses of vitamin D supplementation significantly reduce the risk of T2DM
This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only.
This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of
the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed
description of the concern or complaint, to
service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content
will be removed immediately.
