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JCEM: Long-term effects of metriptine on blood glucose, growth and renal function in patients with Rabson-Mendenhall syndrome

 Last Update: 2021-12-02
 Source: Internet
 Author: User

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Rabson-Mendenhall syndrome (RMS) is the causative mutation caused by the gene of insulin receptor (INSR) are biallelic, insulin resistance leading to diabetes , micro- vascular complications, short stature and growth hormone resistance

Diabetic blood vessels

Recently, a research article was published in the Journal of Clinical Endocrinology & Metabolism, an authoritative journal in the field of endocrine and metabolic diseases.

The researchers compared RMS patients treated with metripstin (≥0.

Over time, the A1c of subjects receiving metripstin was 1.

It can be seen that metripstin changed the natural history of elevated A1c in patients with RMS, resulting in a decrease in A1c levels throughout the long-term follow-up

Metripstin changed the natural history of elevated A1c in patients with RMS, resulting in a decrease in A1c levels throughout the long-term follow-up

Original source:

Marinna C Okawa.

Long-term effects of metreleptin in Rabson -Mendenhall Syndrome on glycemia, growth, and kidney function

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