echemi logo
Product
  • Product
  • Supplier
  • Inquiry
    Home > Active Ingredient News > Endocrine System > JCEM: Mineral Intake and Clinical Symptoms in Adult Patients With Low Phosphorus Emily

    JCEM: Mineral Intake and Clinical Symptoms in Adult Patients With Low Phosphorus Emily

    • Last Update: 2020-06-25
    • Source: Internet
    • Author: User
    Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com
    Hypophosphaemia (HPP) is a rare hereditary metabolic disease characterized by insufficient tissue nonspecific alkaline phosphatase (TNAP), which causes metabolic impairment of phosphorus metabolitesMineral intake in the diet is suspected to affect the clinical symptoms of HPP, but there is no scientific evidence, a cross-sectional matching study collected comprehensive data on nutritional intake of 20 HPP patients and 20 unaffected, age- and gender-matched controls, in a study published recently in journal Of Clinical Endocrinology and Metabolism, an authoritative journal for endocrine and metabolic diseasesDiet information and clinical symptoms were recorded in detail using structural diaries for 7 consecutive daysbalance between baseline data and the type of energy supply nutrientsThe median nutritional intake of phosphorus and calcium in HPP patients decreased significantly compared to the control group, in part because of lower energy consumption in HPP patientsThe absorption differences between Ca/P ratio and Mg, Zn and vitamin B6 were not statistically significantHigh phosphorus intake (?1375 mg/d) and low phosphorus intake (1100 mg/d) were significantly associated with the frequency of neuropsychiatric symptoms (p-0.02)Similarly, very high and very low calcium intake were significantly associated with musculoskeletal (p 0.01), gastrointestinal tract (p.02) and neuropsychiatry (p 0.001) symptomsIncreased Ca/P ratio is associated with increased fatigue/fatigue (p 0.01), while Ca/P reduction is associated with gastrointestinal diseases (p-0.01), so there appears to be a decrease in phosphorus and calcium intake in HPP patients, as well as a decrease in total energy consumptionAbsolute or unbalanced phosphorus and calcium intake is particularly high and very low, both associated with an increasein frequency of clinical symptoms
    This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

    Contact Us

    The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

    Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.