JCEM: Non-alcoholic fatty liver and fibrosis progression are associated with the risk of chronic kidney disease

The relationship between the evolution of non-alcoholic fatty liver (NAFLD) and chronic kidney disease (CKD) is not yet clear
.

Recently, a research article was published in the Journal of Clinical Endocrinology & Metabolism, an authoritative journal in the field of endocrine and metabolic diseases.
Researchers aimed to assess the relationship between changes in NALFD status and the progression of NAFLD fibrosis and the risk of CKD
.

The researchers conducted a community-based prospective study.
Participants included participants who were 40 years of age or older and had no CKD at baseline in 2010, and were followed up after an average of 4.
4 years
.

Correlation between CKD event risk and NAFLD status change

Among the 4042 participants, compared with non-NAFLD patients, NAFLD was associated with an increased risk of CKD (odds ratio, OR=1.
44, 95% confidence interval [CI] of 1.
003-2.
06; P=0.
048), except for the baseline level , Also adjusted for confounding factors, including the evolution of diabetes , hypertension, and obesity
.

It can be seen that NAFLD and fibrosis progression are associated with an increased risk of CKD
.

Original source:

Guangmin Zuo.