JCEM: Relationship between osteoporosis and the risk of Parkinson's disease

Osteoporosis and Parkinson's disease (PD) are often the same, and bone density levels may decrease even in early PD patients.
this may mean that osteoporosis is associated with a higher PD risk.
recently, a study published in Journal of Clinical Endocrinology and Metabolism, an authoritative journal in the field of endocrine and metabolic diseases, aims to determine whether people with osteoporosis have an increased risk of subsequent PD.
researchers conducted retrospective queue studies using Taiwan's National Health Insurance Research Database.
osteoporosis group included 23,495 subjects between the ages of 50 and 80 with osteoporosis between 2002 and 2006.
the control group included 23,495 patients without osteoporosis with a tendency score match.
their tendency scores were calculated using the Logistic regression model, which includes age, gender, comormity, and socioethic status.
risk of PD in the Osteoporosis group (HR) was 1.31 times higher than in the control group (95% CI: 1.13-1.50, p=0.0002).
PD survival rate was also significantly lower in the Osteoporosis group than in the control group (p-0.0004).
gender-specific analysis showed that women with osteoporosis had PD HR (HR of 1.50, 95% CI: 1.27-1.77, p.lt. 0.0001) appears to be higher than males (HR 1.23, 95% CI: 0.93-1.64), p-0.15).
this study suggests that osteoporosis is associated with an increased risk of PD, especially in women.
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