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In a recent study, 27 metabolites, including serum glycine, are related to density (BMD)
.
Recently, a research article was published in the Journal of Clinical Endocrinology & Metabolism, an authoritative journal in the field of endocrine and metabolic diseases.
Researchers aimed to investigate the relationship between serum and urine glycine levels and male BMD, bone microstructure, and fracture risk
.
In the population-based MrOS Swedish study (men 69-81 years old), researchers measured the subjects' serum glycine levels and BMD at baseline (n=965) and follow-up 5 years later (n=546)
.
During follow-up, high-resolution peripheral quantitative computed tomography was used to measure the cortical and trabecular bone parameters of the distal tibia
The relationship between serum glycine levels and BMD
Circulating glycine level is negatively correlated with femoral neck (FN)-BMD
.
A meta-analysis (n=7543) combined the MrOS Swedish data with data from three other cohorts and confirmed that there is a negative correlation between serum glycine levels and femoral neck BMD (FN-BMD) (p=7.
Osteoporosis
It can be seen that serum and urine glycine levels are indirectly related to FN-BMD and cortical bone strength, and directly related to the risk of fractures in men
.
.
Original source:
Original source:Anna L Eriksson.
Serum glycine levels are associated with cortical bone properties and fractures risk in men in this message