 Home > Active Ingredient News > Endocrine System > JCEM: The causal effect of estradiol on bone density

JCEM: The causal effect of estradiol on bone density

 Last Update: 2021-08-03
 Source: Internet
 Author: User

Tags

estrogen blocker women

mineral oil lube

Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

Estradiol is one of the main sex hormones in women, and it plays an important role in the bone health of both men and women
.

Several enzymes are involved in the metabolism of estradiol, but genome-wide association studies ( GWAS ) are rarely conducted to summarize the genetic promoting factors that lead to changes in estrogen levels

GWAS

Recently, a research article was published in the Journal of Clinical Endocrinology & Metabolism, an authoritative journal in the field of endocrine and metabolic diseases.

The study aims to identify the gene locus that affects estradiol levels and estimate the effect of estradiol on bone mineral density (BMD).
The influence of causality

Researchers performed GWAS on male (N=147690) and female (N=163985) estradiol from the UK Biobank (UKB)
.

Estradiol is classified as a binary phenotype; above/below the detection threshold (175pmol/L)

The importance of the body's own estrogen for maintaining bone health in men and women

Original source:

Daniel Schmitz.

et al.
Genome-Wide Association Study of Estradiol Levels, and the Causal Effect of Estradiol on Bone Mineral Density .
JCEM.
2021.
https://doi.
org/10.
1210/clinem/dgab507

Genome-Wide Association Study of Estradiol Levels , and the Causal Effect of Estradiol on Bone Mineral Density in this message

This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

Related Products

Fast Shipping Peptide Semaglutide Tirzepatide Mt2 Angiotensin2 Adipotide Epithalon Icatibant Thymalin Liraglutide Retatrutide

CAS No.: 204656-20-2

Industrial Grade

$15.45-18.54/UNIT FOB

Flibanserin powder CAS 167933-07-5 99% Pure Flibanserin

CAS No.: 167933-07-5

Pharmacy Grade

$5-6/KG FOB

Potassium iodide 99% White Powder Pharmacy Grade OUDA

CAS No.: 7681-11-0

Pharmacy Grade

$2.5-3/KG FOB

Hot Tags

united states jobs(223)

jobs united states(236)

1 year treasury(277)

1 year subscription(296)

announcements today(81)

80 20 company(94)

united states logo(227)

single use technology(195)

healthy food name(42)

ups united states(221)

Hot Articles

The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.