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    Home > Active Ingredient News > Endocrine System > JCEM: The causal relationship between serum thyroid stimulating hormone and obesity

    JCEM: The causal relationship between serum thyroid stimulating hormone and obesity

    • Last Update: 2021-03-26
    • Source: Internet
    • Author: User
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    Some previous epidemiological studies have explored the association between serum thyroid-stimulating hormone (TSH) and obesity characteristics.


    Recently, a research article was published in the Journal of Clinical Endocrinology & Metabolism, an authoritative journal in the field of endocrine and metabolic diseases, which aims to clarify and analyze the causal relationship between serum TSH levels and obesity-related indicators (BMI and obesity).


    The researchers searched the latest genome-wide association study ( GWAS ) on TSH, BMI and obesity to obtain complete statistics.


    GWAS

    Both IVW and MR-Egger results showed that gene-driven serum TSH did not cause changes in BMI or obesity.


    Therefore, considering fT3 together, TSH can be significantly increased by gene-driven increase in BMI .


    Considering fT3 together, TSH can be significantly increased by gene-driven increase in BMI

    Original source:

    Original source:

    Xichang Wang.


    org/10.
    1210/clinem/dgab183" target="_blank" rel="noopener">Causal Association between Serum Thyroid-Stimulating Hormone and Obesity: A Bidirectional Mendelian Randomization Study in this message
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