JCEM: The effect of metabolic syndrome and its parts on fractures

The relationship between metabolic syndrome (MetS) and fracture risk is controversial.
recently, a research paper was published in Journal of Clinical Endocrinology and Metabolism, an authoritative journal in the field of endocrine and metabolic diseases, to explore the relationship between metabolic syndrome (MetS) and fracture risk.
15.9 years of mid-level follow-up, the researchers aimed to determine the effects of metabolic syndrome (MetS) and its components on fracture risk.
7,520 participants over the age of 30 (4,068 women) were included in the study.
results are analyzed using multivariate Cox proportional risk regression analysis.
40.0 per cent and 40.4 per cent, respectively, among male and female participants.
follow-up period, the researchers observed a total of 305 fractures that required hospitalization (males . . . 152).
risk ratio (HR) and 95% confidence interval (CI) for fractures in men and women were 0.72 (0.49-1.05, p=0.08) and 1.38 (0.96-1.98, p=0.08), respectively.
In a fully adjusted model, men with high peri-abdominal blood sugar (FPG) tended to have a lower risk of fractures (0.44-1.02, P-0.06) and in women, a larger waist circumference (WC) was associated with a higher risk of fractures .40 (1.55-3.73).
metS did not affect the risk of fractures in the population over 50 in the aggregated sample, but the greater WC was associated with a higher risk of 1.58 (1.07-2.33).
for hip/pelvic fractures, abdominal obesity (not MetS) is also an important and independent risk factor.
, it can be seen that there are gender differences between mets and their parts and fractures.
women with abdominal obesity had an increased risk of fractures, while men with higher FPG had a lower risk.