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    Home > Active Ingredient News > Endocrine System > JCEM: The efficacy of zoledronic acid in the treatment of glucocorticoid-induced osteoporosis

    JCEM: The efficacy of zoledronic acid in the treatment of glucocorticoid-induced osteoporosis

    • Last Update: 2021-08-03
    • Source: Internet
    • Author: User
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    Glucocorticoids (GC) prescribed to treat chronic pediatric diseases are associated with osteoporotic fractures


    Osteoporosis

    Recently, a research article was published in the Journal of Clinical Endocrinology & Metabolism, an authoritative journal in the field of endocrine and metabolic diseases.


    This multinational, randomized, double-blind, placebo-controlled Phase 3 trial (ClinicaTrials.


    child

    Changes in bone renewal markers in each group from baseline to the 12th month

    The study recruited 34 children (mean age of 12.


    Thus, in GIO children, compared with placebo, LSBMDZ increased significantly within one year after ZA treatment


    Among GIO children, LSBMDZ increased significantly within one year after ZA treatment compared with placebo


    Original source:

    Leanne M Ward.


    Zoledronic acid versus placebo in pediatric glucocorticoid- induced osteoporosis: A randomized double-blind phase 3 trial

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