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In the 20th century, the incidence of many hormone-dependent diseases (including testicular cancer) increased dramatically in all high-income countries
.
This cannot be fully explained by known risk factors
Recently, a research article was published in the Journal of Clinical Endocrinology & Metabolism, an authoritative journal in the field of endocrine and metabolic diseases.
This systematic review assessed the association between EDC exposure and the risk of testicular cancer (seminoma and non-seminoma)
.
According to the PRISMA guidelines, researchers searched PubMed and Embase databases for English-language documents published before December 14, 2020
.
Of the 279 records identified, 19 records met the quality assessment criteria, and 10 records met the criteria for further meta-analysis
The average age at diagnosis of testicular cancer is 31.
9 years
.
The effect of EDC multi-pollutant mixing is not considered
diagnosis
It can be seen that EDC exposure of mothers rather than adult males after birth is associated with a higher risk of testicular cancer, especially non-seminoma
.
However, the quality of research is uneven.
EDC exposure to mothers rather than adult males after birth is associated with a higher risk of testicular cancer, especially non-seminoma
Endocrine Disrupting Chemicals and Risk of Testicular Cancer A Systematic Review and Meta-analysis in this message
